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If phenobarbital and doxycycline are administered concurrently, the clinical reaction to doxycycline must be monitored carefully.A therapeutic anticonvulsant level of phenobarbital during the serum is ten to 25 µg/mL. To attain the blood levels considered therapeutic in little ones, higher per-kilogram dosages are normally essential for phenobarbi
Following oral or parenteral administration, barbiturates conveniently cross the placental barrier and therefore are distributed in the course of fetal tissues with highest concentrations found in the placenta, fetal liver and brain. Fetal blood levels method maternal blood levels following parenteral administration.Alkalinization of urine hastens
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